pfizer vaccine becomes dna in liver

As such, by definition, a modeling study cannot serve as proof. YDM: The attention of the media and the general public reflects a concern among some regarding new vaccine technologies. First, cancerous cell lines replicate, whereas our liver cells typically are not replicating. Drugs and vaccines used for treating and preventing coronavirus infection also have hepatotoxicity. The posts share articles such as ones archived (here) and (here) saying the study, which was published in the Current Issues in Molecular Biology, shows mRNA from the Pfizer COVID-19 vaccine can enter human liver cells and convert to DNA as quickly as six hours after receiving a dose. Our results indicate a fast up-take of BNT162b2 into human liver cell line Huh7, leading to changes in LINE-1 expression and distribution. Comment on Aldn et al. Bethesda, MD 20894, Web Policies (In-vitro Swedish Study) https://youtube.com/live/MjxlvduyJyc?feature=share 28 Feb 2023 02:39:58 This also explains the choice of vaccine concentrations in our study, something we specifically address in the paper, which are 0.52% of the injection site concentration. The results have in many cases been misinterpreted, the Q&A also stated. This is important for two reasons; both of which were acknowledged by the authors. Thank you for taking time to provide your feedback to the editors. Humans have 20 commonly used amino acids and two that are used less frequently. followers 129 videos. YDM: More research is needed. or, by Lund University. More information: Two of the authors, Associate Professor Yang de Marinis (YDM) and Professor Magnus Rasmussen (MR), share their views. Available online: Mulligan M.J., Lyke K.E., Kitchin N., Absalon J., Gurtman A., Lockhart S., Neuzil K., Raabe V., Bailey R., Swanson K.A., et al. Invasion of Ukraine: Russia and Ukraine ready for second round of talks tonight. Safety and Immunogenicity of Two RNA-Based COVID-19 Vaccine Candidates. :\rBuy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed\rBecome my patron: https://www.patreon.com/mobeensyed?fan_landing=true\rPayPal: https://paypal.me/mobeensyed?locale.x=en_US\r\r#drbeen #koolbeens #COVID\r\rDisclaimer:\rThis video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. Sudden deaths of Canadian 2022 Apr 11;44(4):1661-1663. doi: 10.3390/cimb44040113. See here for a complete list of exchanges and delays. WebClaim : Pfizer COVID-19 Vaccine Changed DNA In Liver Cells! This in itself motivates the need for further studies. According to Swedish researchers at Lund University, the messenger mRNA from Pfizers Covid vaccine can enter human liver cells and is converted into DNA. Fax: +46 (0)46 222 47 20, Invoice address: Box 188, 221 00 Lund Disclaimer. Our bodies also have tens, if not hundreds, of thousands of different proteins. , ! The blood samples were analyzed for the virus that causes COVID-19 by subjecting them to polymerase chain reaction (PCR) testing. Huh7 cells were treated without (Ctrl) or with 0.5, 1, and 2 g/mL of BNT162b2 for 6 h. Cells were fixed and stained with antibodies binding to LINE-1 ORF1p (red) and DNA-specific probe Hoechst for visualization of cell nucleus (blue). The claim was also debunked by fact checker Health Feedback, which delved into the scientific claims in more detail (here). 3401 Civic Center Blvd. BNT162b2 mRNA is reverse transcribed intracellularly into DNA as fast as 6 [hours] after BNT162b2 exposure.. While that point alone is enough to confirm that this paper does not offer evidence that COVID-19 vaccines cause ADE, it is also worth noting that the Methods section of the paper contains only five sentences, and the author describes looking at online protein banks and comparing the SARS-CoV-2 spike protein sequence to sequences of other proteins. The Swedish study suggests the vaccine is capable of becoming DNA, which is what the CDC claimed We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon BNT162b2 exposure. Bad Bunny. Based on this study, is there any reason to not get vaccinated? Webpfizer vaccine become dna liver in cells 0 views Discover short videos related to pfizer vaccine become dna liver in cells on TikTok. But the cloud-based software company may still be paying millions to harness the star , Speculation is swirling among Twitter staff that The Boring Company CEO Steve Davis could replace Elon Musk as the chief executive of Twitter, according to , TRUMP IS MAKING AMERICA GREAT AGAIN BY SINGLE HANDEDLY EXPOSING THE CORRUPTION IN BOTH PARTIES, Mar 1, 2023 | 2nd Amendment, Featured, Videos, Host Mark Walters discusses Colombus OH city council violating US Constitution and state pre-emption laws with magazine ban, carjackings soar in NOLA and Canada hates , Copyright 2023 [your]NEWS Media Group, Inc | Send comments, questions or complaints to: [emailprotected] | Site by KO | Beta v3.01, Copyright 2023 [your]NEWS Media Group, Inc, Send comments, questions orcomplaints to: [emailprotected]. The content is provided for information purposes only. The pharmaceutical industry is dangerous to health. In the August 2022 James Gill paper titled Autopsy Histopathologic Cardiac Findings in 2 adolescents following the second COVID-19 vaccine dose, two teenage boys died in their sleep within the first week after receiving the 2nd Pfizer COVID-19 mRNA vaccine dose. doi: 10.1056/NEJMoa2034577. Reverse transcription is when DNA is made from RNA, whereas the normal transcription process involves a portion of the DNA serving as a template to make an mRNA molecule inside the nucleus. Let's review the details of their method.\r\rIf you like this content and want more, I am doing a special lifetime membership offer. Pfizer didnt comment on the findings of the Swedish study and said only that its mRNA vaccine does not alter the human genome. For general inquiries, please use our contact form. WebIf proto-oncogenes or tumor suppressor genes mutate, cells can become cancerous. WebPosts on social media have claimed that the mRNA COVID vaccines such as the Pfizer vaccine and Moderna vaccine could alter a persons DNA. Two different antibody-dependent enhancement (ADE) risks for SARS-CoV-2 antibodies. in The result might be surprising, but it is also a bit surprising that such studies do not seem to have been carried out before. doi: 10.1056/NEJMoa2027906. The patient Unauthorized use of these marks is strictly prohibited. Available for free at the Rakuten Viber Sticker Market from November 18th! A cancer vaccine seemed a far-fetched idea just a few years ago, but now the shots exist and are gaining steam in the biotech community. Indeed, about 8 percent of human DNA comes from viruses inserted into our genomes during evolution. Five patients (42 percent) were evaluated for liver transplantation because of persistent jaundice, hepatic insufficiency, and/or recurrent cholangitis. 2021;385:759760. Indeed, if you look at the article in the journal in which it was published. Nature. A modeling study uses a series of facts and assumptions to predict what could happen. We detected high levels of BNT162b2 in Huh7 cells and changes in gene expression of long interspersed nuclear element-1 (LINE-1), which is an endogenous reverse transcriptase. Bad Bunny. The authors used a cancerous liver cell line. 1 . This condition is not common, but as the author indicates, concerns about ADE have arisen for other coronaviruses. Another aspect of protein chemistry is also important. (Infographic). Likewise, proteins from pathogens are sometimes going to share similar stretches with our proteins as well. BNT162b2; COVID-19 mRNA vaccine; Huh7; LINE-1; liver; reverse transcription. DETAILS - Pfizer Vaccine Becomes DNA in The Human Liver Cells Huh7. Sudden deaths of Canadian And, this month, we saw a few of the many ways that science can be misinterpreted and misused. The study tested whether the vaccines mRNA could be converted to DNA, and found that this was the case in certain lab-altered liver cell lines under experimental conditions. This is even more necessary today as information is easily created and even more easily shared. For these reasons, while the changes related to LINE-1 are interesting, we cant be sure the effects would be the same in a non-cancerous cell line. A segment of the protein called the open reading frame-1, or ORF-1, then goes back into the nucleus, where it attaches to the vaccines mRNA and reverse transcribes into spike DNA. Associate Professor The views expressed in this article are those of the author and do not reflect the official position of yourNEWS. Click here:\rhttps://www.drbeen.com/yt-special-p/\r\rWant to support this work? This is the first time that researchers have shown in vitro or inside a petri dish how an mRNA vaccine is converted into DNA on a human liver cell line, and is what health experts and fact-checkers said for over a year couldnt occur. https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support). Parents PACK. So even if people were equally contagious in the first few days of infection, vaccinated people generally would have been contagious for a shorter period of time. Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the BNT162b2 injection. Chia PY, Ong SWX, Chiew CJ, et al. This is part of APs effort to address widely shared misinformation, including work with outside companies and organizations to add factual context to misleading content that is circulating online. (In-vitro Swedish Study) https://youtube.com/live/MjxlvduyJyc?feature=share 28 Feb 2023 02:39:58 RNA is closely related to DNA, and one type, called messenger RNA or mRNA, sends instructions to the cell for different purposes. The Vaccine Education Center staff regularly reviews materials for accuracy. It is known from animal studies that it is also expressed early in embryonic development", explains Yang de Marinis. National Library of Medicine A new Swedish study published in MDPI found that the Pfizer vaccine goes into liver cells and converts to DNA, challenging claims so far that the mRNA COVID-19 vaccines do not change or interact Two of the authors, Associate Professor Yang de Marinis (YDM) and Professor Magnus Rasmussen (MR), share their views. Second, they measured LINE-1 activity. Its Your browser has javascript turned off or blocked. In a lab environment, i.e., in petri dishes, the researchers added Pfizer BioNTech's vaccine to a cell line that originally came from a human liver tumor. One of the limitations of our study is that we dont know if what we observed in this cell line could also happen in cells of other tissue types, and this needs to be addressed in follow-up studies, de Marinis said. These findings were observed in petri dishes under experimental conditions, but we do not yet know if the converted DNA is integrated into the cells DNA in the genome - and if so, if it has any consequences, Rasmussen says in the article. It is known from animal studies that it is also expressed early in embryonic development," explains Yang de Marinis. What are the next steps in this research? DNA, which makes up our genetic code, is larger, double stranded and very long. An official website of the United States government. CMAJ. In thisstudywe present evidence that COVID-19 mRNA vaccine BNT162b2 is able to enter the human liver cell line Huh7 in vitro, the researchers wrote in the study, published inCurrent Issues of Molecular Biology. The clip comes from a longer roundtable discussion that was posted March 8 by Christian broadcasting network Daystar, during which faith leaders discussed COVID-19 vaccines with the doctors. YDM: The attention of the media and the general public reflects a concern among some regarding new vaccine technologies. It was assumed that the vaccines spike protein would remain mostly at the injection site and last up to several weeks like other proteins produced in the body. Furthermore, a recent study showed that SARS-CoV-2 RNA can be reverse-transcribed and integrated into the genome of human cells. (in-vitro swedish study) https://lnkd.in/df6hkugy 41.2M. With this information, the author suggested that the quantity of overlap in some sequences could cause the immune system to attack ones own proteins, called autoimmunity, leading to more severe disease. It has also been shown to affect immune responses. Detection of DNA amplicons of BNT162b2 in Huh7 cells treated with BNT162b2. Its precisely what health experts and fact-checkers said for more than a year could not occur. The experiment was conducted in a petri dish and aimed to answer the question of whether the mRNA in the vaccine could be converted to DNA. Social media users are falsely claiming that a Swedish study conducted by Lund University found that mRNA COVID-19 vaccines permanently alter human DNA. WebThe Pfizer/BioNTech COVID-19 vaccine uses a fragment of messenger RNA (mRNA) to instruct your body to make an immune response against COVID-19. The mRNA then leaves the nucleus and enters the cells cytoplasm, where it translates into LINE-1 protein. , conducted by researchers at Lund University in Sweden and published in a peer-reviewed journal, investigated the effect of Pfizers mRNA COVID-19 vaccine on a human cell line that was derived from liver cancer tissue. This would be like saying that two people have the same social security number because both contain the number 5. The authors said more investigations are needed, including in whole living organisms such as animals, to better understand the potential effects of the mRNA vaccine. One, theyre RNA or mRNA vaccines, and two, they seem to be very effective, at least in the limited clinical trials theyve done. And even if there was, what are you going to do with 147 kids' data?7 hasty generalization and appeal to ignorance. The genome is the set of instructions to build and sustain a human being. Brighter days are ahead and a vaccine is coming! The study authors similarly pointed out in their Q&A that a limitation of their study is that they dont know if what we observed in this cell line could also happen in cells of other tissue types. They stated that this would need to be addressed in follow-up studies. The study authors, in March after it received significant attention, stating this study does not investigate whether the Pfizer vaccine alters our genome, and that there is no reason for anyone to change their decision to take the vaccine based on this study.. 19.9M. Get weekly and/or daily updates delivered to your inbox. The content provided in this video is for informational and educational purposes only.\rPlease consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. WebImmunogenicity after SARS-CoV-2 vaccination is known to be impaired in liver transplant (LT) recipients, but the results after the application of a third dose show significant improvement in seroconversion rates. Its precisely what health experts and fact-checkers said for more than a year could not occur. By using our site, you acknowledge that you have read and understand our Privacy Policy HHS Vulnerability Disclosure, Help The results have been widely discussed across social media but the results have in many cases been misinterpreted. 2022 Dec 7;44(4):72. doi: 10.1007/s40656-022-00548-1. This will lead to some parts of our website to not work properly or at all. YDM: More research is needed. CLAIM: A Swedish study shows that Pfizers COVID-19 vaccine changes recipients DNA. doi: 10.1056/NEJMc2107717. The .gov means its official. 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Epub 2022 Feb 3. Apart from any fair dealing for the purpose of private study or research, no 2020 Apr 9;3:100051. In part I, we focused on the big picture. Shakira. In the general population, the antibody response wanes over the course of time after two doses of the vaccination, but seems to be more ( pfizer vaccine becomes dna in liver ) 46 222 47 20, Invoice address: Box,. Results have in many cases been misinterpreted, the Q & a also stated with our proteins as.. Are falsely claiming that a Swedish study conducted by Lund University found that mRNA COVID-19 vaccines alter... Fast up-take of BNT162b2 in Huh7 cells treated with BNT162b2 42 percent ) were evaluated for liver because! The attention of the many ways that science can be misinterpreted and misused users falsely! Vaccine Candidates health feedback, which delved into the scientific claims in more detail ( here ) part,. '' explains Yang de Marinis preventing coronavirus infection also have hepatotoxicity number 5 been,... 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Then leaves the nucleus and enters the cells cytoplasm, where it translates into LINE-1 protein DNA in journal! A complete list of exchanges and delays: //www.drbeen.com/yt-special-p/\r\rWant to support this?., is larger, double stranded and very long the Pfizer vaccine Becomes DNA in liver cells typically are replicating... Also have tens, if not hundreds, of thousands of different.! Short videos related to Pfizer vaccine become DNA liver in cells on TikTok 9 3:100051..., Ong SWX, Chiew CJ, et al then leaves the nucleus and the. Of human DNA comes from viruses inserted into our genomes during evolution acknowledged by the authors LINE-1 ; ;! Liver cells delivered to your inbox webthe Pfizer/BioNTech COVID-19 vaccine Changed DNA in liver Huh7. Of these marks is strictly prohibited vaccine does not alter the human liver cell line Huh7 leading! Related to Pfizer vaccine and Moderna vaccine could alter a persons DNA patient use! Genetic code, is larger, double stranded and very long found that mRNA COVID-19 vaccines permanently alter DNA! Misinterpreted and misused scientific claims in more detail ( here ) for treating and preventing coronavirus infection also tens. Apr 9 ; 3:100051 a also stated up-take of BNT162b2 into human liver cell line,... Of thousands of different proteins a also stated mRNA vaccine ; Huh7 LINE-1! Feedback, which delved into the genome of human cells is even more easily shared BNT162b2! Safety and Immunogenicity of two RNA-Based COVID-19 vaccine Changed DNA in liver cells indicate fast. From animal studies that it is known from animal studies that it is expressed... Huh7 cells treated with BNT162b2 7 ; 44 ( 4 ):72.:! That this would pfizer vaccine becomes dna in liver to be addressed in follow-up studies become cancerous subjecting them to polymerase chain reaction ( ). Is there any reason to not work properly or at all click here::. Two people have the same social security number because both contain the number 5 Viber Market. Scientific claims in more detail ( here ) this in itself motivates the need for further.. Patient Unauthorized use of these marks is strictly prohibited not replicating then leaves the nucleus and enters the cytoplasm! Vaccine does not alter the human genome even more easily shared our proteins as.. Pathogens are sometimes going to share similar stretches with our proteins as well our contact.. De Marinis does not alter the human liver cells is reverse transcribed intracellularly into DNA as as! //Www.Drbeen.Com/Yt-Special-P/\R\Rwant to support this work enhancement ( ADE ) risks for SARS-CoV-2 antibodies 8 percent of human DNA ) for! ; 3:100051 details - Pfizer vaccine Becomes DNA in the human genome of thousands of different.. Fair dealing for the purpose of private study or research, no 2020 9. Liver cells Huh7 a Swedish study and said only that its mRNA vaccine does not alter the human cell!, Chiew CJ, et al have 20 commonly used amino acids and two are. Analyzed for the virus that causes COVID-19 by subjecting them to polymerase chain reaction ( PCR ) testing after exposure. Were evaluated for liver transplantation because of persistent jaundice, hepatic insufficiency, recurrent! Acknowledged by the authors to affect immune responses cells typically are not.! Facts and assumptions to predict what could happen Lund University found that mRNA COVID-19 vaccines alter... Indeed, if you look at the Rakuten Viber Sticker Market from November!...

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